Scole United will begin life in the top flight this afternoon with a daunting clash against champions Acle United.

Last season's First Division runners-up could not have been handed a harder start following promotion as they aim to prove they belong among the Almary Green Anglian Combination's elite. Acle have lifted the Premier Division crown for three seasons in a row – and unsurprisingly – are the favourites to retain the Sterry Cup this season.

The only side to stop their dominance of the Step Seven set-up, Spixworth, begin their campaign with a home fixture against Norwich CEYMS. Spixworth beat Acle 3-1 in the Don Frost Cup final to prevent their opponents from retaining their trophy and completing an Anglian Combination double.

Elsewhere, Harleston Town host St Andrews, Kirkley & Pakefield Reserves entertain 2014-15 runners-up Blofield United and Long Stratton welcome Caister.

In the second tier, Beccles Town – who narrowly missed out on going up last term – begin a new era under the stewardship of joint managers Neil Hurren and Steven Batt. They replace Gaven Tipple, who moved up the pyramid to take over non-league Kirkley & Pakefield, and open their doors to Hellesdon on the opening weekend.

Wymondham Town and Sheringham kick-start their quests to get back into the Premier Division – following relegation – by locking horns against each other. The former are at home in the fixture.

Newly promoted Mulbarton Wanderers got their Premier League campaign off to an excellent start on Friday night when they beat visitors Wroxham Reserves 3-0. Dersingham won by the same scoreline at Mattishall while in Division One there was a stunning derby win for Aylsham, who won 7-0 at Holt United. On Thursday evening Reepham Town opened the new campaign by beating Cromer Town 2-1 at Stimpsons Piece.