The A47 has now re-opened after a crash near Wisbech.
It was closed in both directions for more than two hours after a collision involving three vehicles at the junction with Meadowgate Lane, on the outskirts of Wisbech. A woman and a child were injured.
Police say the driver of one of the vehicles involved fled the scene of the crash on foot. A spokesman said: "Efforts are ongoing to trace him."
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Norfolk fire service said appliances from Wisbech and Downham Market attended the collision.
It said crews used hydraulic rescue equipment to free casualties.
The East of England Ambulance Service said two ambulances and a rapid response vehicle were sent to the crash scene.
A spokesman said: "We treated a child and a woman at the scene and transported them to Peterborough General Hospital for further treatment."
The road was closed between the A1101 Elm roundabout and the junction with the B198 Lynn Road at Walsoken. There wre long tailbacks and drivers faced 30-minute delays.
The junction with Meadowgate Lane is a notorious accident blackspot. Traffic pulls straight out of a country lane onto the main A47.
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