Fears over isolation through the cold months have sparked calls urging people to regularly check in on their friends, neighbours and loved ones.
With the winter months now well upon us, health bosses fear people will become more and more isolated - particularly in older age groups.
It has sparked the launch of a campaign - called Warm and Well - encouraging people in the region to "winter-proof" their lifestyles
The campaign had included a plea for people to keep checking in on their loved ones - as well as urging people to take up flu and Covid-19 jabs to avoid illness.
Bill Borrett, chairman of the Norfolk and Waveney integrated care partnership, said: "People can feel more isolated during winter months as they stay indoors and this can impact their mental health.
"We can all help by checking in regularly on friends, family and neighbours, particularly during cold snaps.
"Connecting with your local community can make a real difference for those living by themselves - plus it can help lift your own mood as well."
The campaign is also geared at trying to prevent people needing to attend hospital - at a time when the NHS is already battling sustained pressure.
It aims to do so by offering advice on how people can care for their loved ones at home and prevent the type of sickness that requires hospital admission.
Tricia D'Orsi, director of nursing at NHS Norfolk and Waveney, meanwhile, has encouraged people to take up flu and Covid-19 vaccines if offered.
She said: "Vaccination against seasonal illness is a really important way to help keep you and your loved ones safe and healthy this winter.
"Vaccination is a safe and effective way to help protect people who are at risk of getting seriously ill and to help keep people out of hospital over the winter."
For more information on the campaign, visit www.winterwellnorfolkwaveney.co.uk
