They are a group of 50 mums who all share an often challenging, but always rewarding aspect of their lives - they all have a child with Down syndrome.

Eastern Daily Press: An image from the video 50 Mums | 50 Kids | 1 Extra Chromosome, featuring mums and their children with Down Syndrome. Pictured is Lisa Rogers with her son, Cosmo, four. Picture: SUPPLIED BY LISA ROGERSAn image from the video 50 Mums | 50 Kids | 1 Extra Chromosome, featuring mums and their children with Down Syndrome. Pictured is Lisa Rogers with her son, Cosmo, four. Picture: SUPPLIED BY LISA ROGERS (Image: Archant)

And now these women, and their children, have joined forces to create a tear-jerking karaoke video to mark World Down Syndrome Day on March 21.

Among them are Lisa Rogers, from Gresham, and her four-year-old son Cosmo.

Miss Rogers said filming her part of the video had been an 'amazing' experience.

She said: 'When a dad in the group pulled all those clips together, the result was astonishing - a guaranteed positive tear-jerker that visualised every conceivable message about disability, diversity and inclusion without having to say a word.'

The video, titled '50 Mums | 50 Kids | 1 Extra Chromosome,' shows each mum and child performing a 'singing hands' 'carpool karaoke' signed with Makaton, a simplified form of British Sign Language.

They 'sing' A Thousand Years, by Christina Perri, which featured in the twilight films.

The group contacted Ms Perri to get permission to use the song, and Miss Rogers said they were bowled over by the response from her husband, Paul Costabile.

She said: 'Within an hour, the LA-based couple were declaring their heartfelt support for the idea.

'And in a bizarre twist of fate and serendipity, Paul Costabile, went on to declare that he is a life-long advocate of children with special needs, in particular Down syndrome, and had in fact produced the iconic film 'More Alike Than Different' with his sister for the exact same event - World Down Syndrome Day in 2015.'

Miss Rogers said the video had already received a flood of messages of praise and support.

Down syndrome is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. Its effects can include physical growth delays and mild to moderate intellectual disability.

The mums are all part of a Facebook group known as Designer Genes.

Meanwhile, Norwich City Hall and Norwich Castle will both mark World Down Syndrome Day by lighting up in blue and yellow.

Find this story online at www.northnorfolknews.co.uk to watch the video.